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ISBN-10: 1464126143
ISBN-13: 9781464126147 978-1464126147
Molecular Biology- Principles and Practice 2e
Cox et. al
Chapter 4
- Which of the following amino acids has an aromatic R group?
- aspartate
- proline
- threonine
- tyrosine
- arginine
Answer: D
Section: 4.1
Level: Easy
Blooms: Remembering
- Which of the following amino acids has a nonpolar thioether R group?
- cysteine
- serine
- tryptophan
- methionine
- None of the choices given is correct.
Answer: D
Section: 4.1
Level: Medium
Blooms: Remembering
- Which of the following amino acids is/are negatively charged at physiological pH?
- serine
- aspartate
- glutamate
- serine, aspartate, and glutamate
- aspartate and glutamate
Answer: E
Section: 4.1
Level: Medium
Blooms: Understanding
- Considering normal human blood ranges from pH 7.35 to pH 7.45, Table 4.1 predicts that:
- the R group of aspartate is protonated.
- the R group of glutamate is protonated.
- the R group of arginine is protonated.
- the R group of lysine is acidic.
- the R group of arginine is acidic.
Answer: C
Section: 4.1
Level: Hard
Blooms: Understanding
- The flexibility of the polypeptide backbone:
- allows maximum rotation of the unbranched R groups.
- allows resonance between trans and cis configurations.
- is limited by the resonance between the alpha carbon and carboxyl oxygen.
- is limited by resonance between the carboxyl oxygen and amide nitrogen.
- is determined by balance between polar and nonpolar R groups.
Answer: D
Section: 4.1
Level: Medium
Blooms: Understanding
- A Ramachandran plot shows the sterically limited rotational domains:
- between proline and noncylic amino acids.
- between polar and nonpolar R groups.
- of an R group with respect to the neighboring R groups.
- of an R group with respect to the polypeptide backbone.
- that two polypeptide chains can occupy.
Answer: D
Section: 4.1
Level: Medium
Blooms: Understanding
- At pH 7, a peptide with the sequence G-M-G-V-S-D-P-D-A has a net charge of:
- -3
- -2
- -1
- +1
- +2
Answer: B
Section: 4.1
Level: Medium
Blooms: Applying
- At pH 11, a peptide with the sequence G-M-G-V-S-D-P-D-A has the net charge of:
- -3
- -2
- -1
- +1
- +2
Answer: A
Section: 4.1
Level: Hard
Blooms: Applying
- The ? helix contains ______________ amino acids residues per turn. One full turn of the ? helix is ______________ long.
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